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Regarding treatment, treatment of chronic HCV infection with peginterferon + ribavirin showed variable efficacy depending on the genotype with sustained virological response (SVR) rates of 4258% 21,22,23 , 80%, 66% 24 or 6369% 25 for GT1, GT2, GT3 or GT4, respectively

Although several of the most promising senolytics are already being evaluated in preclinical studies, senolytics are still relatively uncommon and their underlying mechanisms remain largely unknown new classes need to be identified

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doi: 10.1007/s40618-015-0404-6 29 HabibZAHavstadSLWellsKDivineGPladevallMWilliamsLK